Quotes from Ben Goldacre

In an ideal world, you might imagine that scientific papers were only cited by academics on the basis of their content. This might be true. But lots of other stuff can have an influence.

I agree, the world would be a better place if doctors were less enthusiastic about adopting very new drugs.

Positive findings are around twice as likely to be published as negative findings. This is a cancer at the core of evidence-based medicine.

Yes. I'm a doctor, an epidemiologist, and lots of my professional colleagues flip back and forth between industry and medical roles. I know them; they are not bad people. But it is possible for good people in bad systems to do things that inflict enormous harm.

There are many differences between medicine and teaching, but they have much in common. Both involve craft and personal expertise, learned through experience; but both can be informed by the experience of others.

Transparency and detail are everything in science.

Real science is all about critically appraising the evidence for somebody else's position.

Teaching needs an ecosystem that supports evidence-based practice. It will need better systems to disseminate the results of research more widely, but also a better understanding of research, so that teachers can be critical consumers of evidence.

Bad things happen when problems are protected by a force field of tediousness.

When you prescribe a new drug, often you are prescribing something that has only been tested in a few thousand people for a very short period of time, perhaps only six months, and that's not long enough to know whether there are any medium- or long-term side effects.

I spend a lot of time talking to people who disagree with me - I would go so far as to say that it's my favourite leisure activity.

Positive findings are around twice as likely to be published as negative findings. This is a cancer at the core of evidence-based medicine.

The placebo effect is one of the most fascinating things in the whole of medicine. It's not just about taking a pill, and your performance and your pain getting better. It's about our beliefs and expectations. It's about the cultural meaning of a treatment.

Real science is all about critically appraising the evidence for somebody else's position.

Alternative therapists don't kill many people, but they do make a great teaching tool for the basics of evidence-based medicine, because their efforts to distort science are so extreme.

Amazing things happen when you pull individual pieces of information together into larger linked datasets: meaning emerges, as you produce facts from figures.

The value of a scientific publication goes beyond this simple benefit, of all relevant information appearing, unambiguously, in one place. It's also a way to communicate your ideas to your scientific peers, and invite them to express an informed view.

Data is the fabric of the modern world: just like we walk down pavements, so we trace routes through data, and build knowledge and products out of it.

If you put me in charge of the medical research budget, I would cancel all primary research, I would cancel all new trials, for just one year, and I would spend the money exclusively on making sure that we make the best possible use of the clinical evidence that we already have.

Science has authority, not because of white coats, or titles, but because of precision and transparency: you explain your theory, set out your evidence, and reference the studies that support your case.

Science isn't about authority or white coats; it's about following a method. That method is built on core principles: precision and transparency; being clear about your methods; being honest about your results; and drawing a clear line between the results, on the one hand, and your judgment calls about how those results support a hypothesis.

In general, drug companies are reasonably good at developing new treatments, and there's also a lot of good in the industry.

Doctors and patients need as much data as possible to make an informed decision about what treatment is best.

There is this peculiar blind spot in the culture of academic medicine around whether withholding trial results is research misconduct. People who work in any industry can reinforce each others' ideas about what is okay.