Quotes About Inactivation

The idea that cancer genes are sitting inside each and every one of our chromosomes, just waiting to be corrupted or inactivated and thereby unleashing cancer, is, of course, one of the seminal ideas of oncology.

Whereas cells in men have just a single, maternal X chromosome, cells in women have both a maternal and a paternal X chromosome. Female cells inactivate one of the two X chromosomes, resulting in a mosaic of cells with distinct combinations of gene variants. This variety could result in an immunity advantage compared to the more fixed expression in males.51