Quotes About P53

The research community became fixated on an 'accelerator' model of cancer – one in which the normal mechanism of cell division is being actively reprogrammed by these 'rogue' genes, the oncogenes, to go into overdrive, thus causing the cells to proliferate wildly. This was the mindset at the time p53 was discovered in 1979.

This means that from a molecular viewpoint there is one basic condition to get a cancer: p53 must be switched off. If p53 is on, and hence functioning properly, cancer will not develop.