Quotes About Allele

Natural selection may usually be safely regarded as the differential survival of replicators relative to their alleles.

The word allele is nowadays customarily used of cistrons but it is clearly easy, and in the spirit of this chapter, to generalize it to any portion of chromosome.

The point is the obvious one that selection at any one locus is not independent of selection at other loci.

ApoE ?2 is relatively rare, but if you inherit this allele, you're more likely to develop Alzheimer's disease later in life. ApoE ?3 is the most common allele, but it's believed to neither increase nor decrease your risk. ApoE ?4, however, is the one typically mentioned in the media and feared the most. In

K. Kidd et al., An Historical Perspective on 'The World-Wide Distribution of Allele Frequencies at the Human Dopamine D4 Receptor Locus,' Human Genetics, 133 (2014): 431.

While the Environmental Genome Project does not seek to assign allele frequencies, we are aware of the importance of accurate allele frequency estimates for future epidemiologic studies and the large sample sizes such estimates will require.

It is only when you have average or low levels of cholesterol that being a carrier of "bad" allele 4 puts you at a greater risk than others with the same cholesterol level.

I could answer by telling you that such selective sweeps create a valley of genetic diversity around the site under selection, that they leave a deficit of extreme allele frequencies (low or high) at linked sites and an increase in linkage disequilibrium in flanking regions—but that doesn't tell you much unless you're a geneticist.

While the Environmental Genome Project does not seek to assign allele frequencies, we are aware of the importance of accurate allele frequency estimates for future epidemiologic studies and the large sample sizes such estimates will require.

As a dominant trait.

Rhesus monkeys (Suomi 2000) that individuals who carry the "short" allele of the 5-HTT gene are significantly more severely affected by maternal deprivation than are individuals with the "long" allele