Quotes About Lysosomes

The possibility that lysosomes might accidentally become ruptured under certain conditions, and kill or injure their host-cells as a result, was considered right after we got our first clues to the existence of these particles.

Intermittent fasting definitely and massively increases autophagy. And thanks to our caveman history, it thrived. In times of little food, lysosomes would race around the body looking for damaged cells, pre-diseased cells, and cells which weren't doing much. It would chop them apart - into their smallest parts - and either burn them for energy, or use them to repair other areas. Simply, it would perform miracles without any outside help.

The problem of different sensitivities of distinct protein groups to lysosomal inhibitors has remained unsolved and may have served as an important trigger in the future quest for a non-lysosomal proteolytic system that may be involved in at least certain aspects of intracellular protein degradation.

The development of methods to monitor protein dynamics in cells together with the discovery of specific and general lysosomal inhibitors have resulted in the identification of different classes of cellular proteins, long- and short-lived, and the findings of the differential effects of the inhibitors on these groups.