Quotes from Robert M. Sapolsky

The childhood capacity for empathy progresses from feeling someone's pain because you are them, to feeling for the other person, to feeling as them.

Obviously, oxytocin and vasopressin are the grooviest hormones in the universe. Pour them into the water supply, and people will be more charitable, trusting, and empathic. We'd be better parents and would make love, not war (mostly platonic love, though, since people in relationships would give wide berths to everyone else). Best of all, we'd buy all sorts of useless crap, trusting the promotional banners in stores once oxytocin starts spraying out of the ventilation system.

Powerful support for an amygdaloid role in fear processing comes from post-traumatic stress disorder (PTSD). In PTSD sufferers the amygdala is overreactive to mildly fearful stimuli and is slow in calming down after being activated.13 Moreover, the amygdala expands in size with long-term PTSD.

In a study of employees throughout the world working for the same multinational bank, what was the most important reason cited to help someone? Among Americans it was that the person had previously helped them; for Chinese it was that the person was higher ranking; in Spain, that they were a friend or acquaintance.

when you think categorically, you have trouble seeing how similar or different two things are. If you pay lots of attention to where boundaries are, you pay less attention to complete pictures.

In general, our morally tinged cultural institutions—religion, nationalism, ethnic pride, team spirit—bias us toward our best behaviors when we are single shepherds facing a potential tragedy of the commons. They make us less selfish in Me versus Us situations. But they send us hurtling toward our worst behaviors when confronting Thems and their different moralities.

stress weakens frontal connections with the hippocampus—essential for incorporating the new information that should prompt shifting to a new strategy—while strengthening frontal connections with more habitual brain circuits.

Stress can be bad for you. We no longer die of smallpox or the plague and instead die of stress-related diseases of lifestyle, like heart disease or diabetes, where damage slowly accumulates over time. It is understood how stress can cause or worsen disease or make you more vulnerable to other risk factors. Much of this is even understood on the molecular level. Stress can even cause your immune system to abnormally target hair follicles, causing your hair to turn gray.

Males who do extreme amounts of exercise, such as professional soccer players and runners who cover more than 40 or 50 miles a week, have less LHRH, LH, and testosterone in their circulation, smaller testes, less functional sperm. They also have higher levels of glucocorticoids in their bloodstreams, even in the absence of stress. (A similar decline in reproductive function is found in men who are addicted to opiate drugs.)

Look at systematic patterns of cultural variation as they pertain to the best and worst of our behaviors. Explore how different types of brains produce different culture and different types of culture produce different brains. In other words, how culture and biology coevolve.3 See the role of ecology in shaping culture.

Fear is the vigilance and the need to escape from something real. Anxiety is about dread and foreboding and your imagination running away with you. Much as with depression, anxiety is rooted in a cognitive distortion. In this case, people prone toward anxiety overestimate risks and the likelihood of a bad outcome.

The insula activates when we eat a cockroach or imagine doing so.

Someone does something lousy and selfish to you in a game, and the extent of insular and amygdaloid activation predicts how much outrage you feel and how much revenge you take.

Castration decreases sexual urges in the subset of sex offenders with intense, obsessive, and pathological urges. But otherwise castration doesn't decrease recidivism rates; as stated in one meta-analysis, "hostile rapists and those who commit sex crimes motivated by power or anger are not amenable to treatment with [the antiandrogenic drugs].

Like so many other animals, we have an often-frantic need to conform, belong, and obey. Such conformity can be markedly maladaptive, as we forgo better solutions in the name of the foolishness of the crowd.

In a typical study, higher testosterone levels would be observed in those male prisoners with higher rates of aggression. But being aggressive stimulates testosterone secretion; no wonder more aggressive individuals had higher levels.

Thus there's dopaminergic activation during schadenfreude—gloating over an envied person's fall from grace.

People see essentialism embedded in bloodlines—i.e., genes.

the average level of happiness increases in old age; fewer negative emotions occur and, when they do, they don't persist as long. Connected to this, brain-imaging studies show that negative images have less of an impact, and positive images have more of an impact on brain metabolism in older people, as compared to young.

Whenever you inhale, you turn on the sympathetic nervous system slightly, minutely speeding up your heart. And when you exhale, the parasympathetic half turns on, activating your vagus nerve in order to slow things down (this is why many forms of meditation are built around extended exhalations).

And their brains? Decreased total brain size, gray matter, white matter, frontal cortical metabolism, connectivity between regions, sizes of individual brain regions. Except for the amygdala. Which is enlarged. That pretty much says it all.

increasing cognitive loadfn8 should make people more conservative. This is precisely the case. The time pressure of snap judgments is a version of increased cognitive load. Likewise, people become more conservative when tired, in pain or distracted with a cognitive task, or when blood alcohol levels rise.

if you want to increase your chances of avoiding stress-related diseases, make sure you don't inadvertently allow yourself to be born poor.

Basically, your heart is just a dumb, simple mechanical pump, and your blood vessels are nothing more exciting than hoses.