Quotes from Robert M. Sapolsky

What do children need from their mothers?": love, warmth, affection, responsiveness, stimulation, consistency, reliability. What is produced in their absence? Anxious, depressed, and/or poorly attached adults.

Kids learn dichotomies in the absence of any ill intent. When a kindergarten teacher says, "Good morning, boys and girls," the kids are being taught that dividing the world that way is more meaningful than saying, "Good morning, those of you who have lost a tooth and those of you who haven't yet.

Genes have plenty to do with behavior. Even more appropriately, all behavioral traits are affected to some degree by genetic variability.65 They have to be, given that they specify the structure of all the proteins pertinent to every neurotransmitter, hormone, receptor, etc. that there is. And they have plenty to do with individual differences in behavior, given the large percentage of genes that are polymorphic, coming in different flavors. But their effects are supremely context dependent.

Elie Wiesel, el ganador del Premio Nobel y superviviente de un campo de concentración: «Lo contrario al amor no es el odio; lo contrario es la indiferencia». Las biologías del amor fuerte y del odio fuerte son parecidas en muchos aspectos, tal como veremos.

When deontologism and consequentialism contemplate trolleys, the former is about moral intuitions rooted in the vmPFC, amygdala, and insula, while the latter is the domain of the dlPFC and moral reasoning. Why is it that our automatic, intuitive moral judgments tend to be nonutilitarian? Because, as Greene states in his book, "Our moral brains evolved to help us spread our genes, not to maximize our collective happiness.

Another study explored the neurobiology of conforming.16 To simplify, a subject is part of a group (where, secretly, the rest are confederates); they are shown "X," then asked, "What did you see?" Everyone else says "Y." Does the subject lie and say "Y" also? Often. Subjects who stuck to their guns with "X" showed amygdala activation.

The amygdala also helps mediate both innate and learned fear.18 The core of innate fear (aka a phobia) is that you don't have to learn by trial and error that something is aversive. For example, a rat born in a lab, who has interacted only with other rats and grad students, instinctually fears and avoids the smell of cats.

To cite a quote attributed to Oscar Wilde, "Morality is simply the attitude we adopt towards people whom we personally dislike." It's Us versus Them framed morally, and the importance of what Greene calls "the Tragedy of Commonsense Morality" is shown by the fact that most intergroup conflicts on our planet ultimately are cultural disagreements about whose "right" is righter.

The dichotomy between innate and learned fear is actually a bit fuzzy.19 Everyone knows that humans are innately afraid of snakes and spiders. But some people keep them as pets, give them cute names.fn13 Instead of inevitable fear, we show "prepared learning"—learning to be afraid of snakes and spiders more readily than of pandas or beagles.

The evolutionarily ancient central amygdala plays a key role in innate fears. Surrounding it is the basolateral amygdala (BLA), which is more recently evolved and somewhat resembles the fancy, modern cortex. It's the BLA that learns fear and then sends the news to the central amygdala.

The most convincing data concern rare humans with damage restricted to the amygdala, either due to a type of encephalitis or a congenital disorder called Urbach-Wiethe disease, or where the amygdala was surgically destroyed to control severe, drug-resistant seizures originating there.5 Such individuals are impaired in detecting angry facial expressions (while being fine at recognizing other emotional states—stay tuned).

Conversely, instruct subjects to "carefully consider" their decision, or prime them to value reflection over intuition, and they'd be more selfish. The more time to think, the more time to do a version of "Yes, we all agree that cooperation is a good thing . . . but here is why I should be exempt this time"—what the authors called "calculated greed.

The sensory cortex and visual cortex are far away from each other. How do those tactile neurons "know" (a) that there's vacant property in the visual cortex; (b) that hooking up with those unoccupied neurons helps turn fingertip information into "reading"; and (c) how to send axonal projections to this new cortical continent? All are matters of ongoing research.

when we get into a physiological uproar and activate the stress-response for no reason at all, or over something we cannot do anything about, we call it things like "anxiety," "neurosis," "paranoia," or "needless hostility." Thus, the stress-response can be mobilized not only in response to physical or psychological insults, but also in expectation of them.

If people around you smell scared, your brain tilts toward concluding that you are too.

As emphasized in the last chapter, epigenetic changes can be multi-generational.8 Dogma was that all the epigenetic marks (i.e., changes in the DNA or surrounding proteins) were erased in eggs and sperm. But it turns out that epigenetic marks can be passed on by both (e.g., make male mice diabetic, and they pass the trait to their offspring via epigenetic changes in sperm).

Cómo he llegado a esto? ¿Cuándo se volvió tan importante para mí el hecho de pisar terreno sólido y familiar? ¿Cómo he llegado a convertirme en uno de esos tipos que compran antologías tipo lo mejor de que anuncia en la televisión a altas horas de la noche?

Edward Tylor, a distinguished nineteenth-century cultural anthropologist. For him culture is "that complex whole which includes knowledge, belief, art, morals, law, custom, and any other capabilities and habits acquired by man [sic] as a member of society.

the opposite of play is not work—it's depression.

you can't begin to understand things like aggression, competition, cooperation, and empathy without biology; I say this for the benefit of a certain breed of social scientist who finds biology to be irrelevant and a bit ideologically suspect when thinking about human social behavior.

There's support for the idea—three of my favorites are that (a) forcing depressed people to smile makes them feel better; (b) instructing people to take on a more "dominant" posture makes them feel more so (lowers stress hormone levels); and (c) muscle relaxants decrease

In our world riddled with male violence, the problem isn't that testosterone can increase levels of aggression. The problem is the frequency with which we reward aggression.

by the time you finish this book, you'll see that it actually makes no sense to distinguish between aspects of a behavior that are "biological" and those that would be described as, say, "psychological" or "cultural." Utterly intertwined.

I can't really imagine how to live your life as if there is no free will. It may never be possible to view ourselves as the sum of our biology. Perhaps we'll have to settle for making sure our homuncular myths are benign, and save the heavy lifting of truly thinking rationally for where it matters—when we judge others harshly.