Quotes from David Perlmutter

The culprit is sugar and carbohydrates.

brain-derived neurotrophic factor," or BDNF. BDNF plays a key role in creating new neurons. But beyond its role in neurogenesis, BDNF protects existing neurons, ensuring their survivability

Aerobic exercise in particular not only turns on genes linked to longevity, but also targets the BDNF gene, the brain's "growth hormone.

our brain's healthy functioning requires regular physical activity despite the passage of time and ills of the aging process.

To quote Gary Taubes, "In fact, we can define this mild ketosis as the normal state of human metabolism when we're not eating the carbohydrates that didn't exist in our diets for 99.9 percent of human history. As such, ketosis is arguably not just a natural condition but even a particularly healthful one."28

Mantener el orden en lugar de corregir el desorden es el principio máximo de la sabiduría. Curar la enfermedad después de que ha aparecido es como cavar un pozo cuando uno tiene sed, o forjar armas después de que la guerra ha comenzado. NEI JING, siglo II d. C.

Modern grains are silently destroying your brain.

challenging the mind fortifies new neural networks. Much in the way our muscles gain strength and functionality when physically challenged through exercise, the brain similarly rises to the challenges of intellectual stimulation.

Dr. George Mann, a researcher with the Framingham Heart Study, to go on record stating: The diet heart hypothesis that suggests that a high intake of fat or cholesterol causes heart disease has been repeatedly shown to be wrong, and yet, for complicated reasons of pride, profit, and prejudice, the hypothesis continues to be exploited by scientists, fund-raising enterprise, food companies, and even governmental agencies. The public is being deceived by the greatest health scam of the century.

foods produce as much of a surge in blood glucose

cholesterol and transport it to the neuron, where it performs critically important functions.

And now we have the evidence in the scientific literature to prove that when cholesterol levels are low, the brain simply doesn't work well; individuals with low cholesterol are at much greater risk for dementia and other neurological problems.

to the brain? One of the most common ways is through physical modification by glucose. Sugar molecules attach themselves to LDL and change the molecule's shape, rendering it less useful while increasing free radical production.

The following grains and starches are gluten-free: amaranth arrowroot buckwheat corn millet potato quinoa rice sorghum soy tapioca teff The following foods often contain gluten: baked beans (canned) beer blue cheeses bouillons/broths (commercially prepared) breaded foods cereals chocolate milk (commercially prepared) cold cuts communion wafers egg substitute energy bars flavored coffees and teas

Lifestyle factors that stimulate this process include eating a diet that derives more energy or calories from fat than from carbohydrate (a central theme of Grain Brain

Several natural compounds that turn on antioxidant and detoxification pathways through activation of the Nrf2 system have been identified. Among these are curcumin from turmeric, green tea extract, silymarin (milk thistle), bacopa extract, DHA, sulforaphane (contained in broccoli), and ashwagandha. Each

THE GLUTEN POLICE The following grains and starches contain gluten: barley bulgur couscous farina graham flour kamut matzo rye semolina spelt triticale wheat wheat germ

I'm here to tell you that the fate of your brain is not in your genes. It's not inevitable. And if you're someone who suffers from another type of brain disorder, such as chronic headaches, depression, epilepsy, or extreme moodiness, the culprit may not be encoded in your DNA. It's in the food you eat.

all manner of disease is rooted in inflammation run amok, and your immune system controls inflammation.

ApoE ?2 is relatively rare, but if you inherit this allele, you're more likely to develop Alzheimer's disease later in life. ApoE ?3 is the most common allele, but it's believed to neither increase nor decrease your risk. ApoE ?4, however, is the one typically mentioned in the media and feared the most. In

diet will remove all the fat from your body because the brain is entirely fat. Without a brain, you might look good, but all you could do is run for public office. — GEORGE BERNARD SHAW

We can break down fat into specialized molecules called ketones, and one in particular that I've already mentioned—beta-hydroxybutyrate (beta-HBA)—is a superior fuel for the brain.

A purely ketogenic diet is one that derives 80 to 90 percent of calories from fat, and the rest from carbohydrate and protein.

Indeed, Dr. Cahill and other researchers have determined that beta-HBA, which is easily obtainable just by adding coconut oil to your diet, improves antioxidant function, increases the number of mitochondria, and stimulates the growth of new brain cells. In chapter 5 we