Quotes from David Perlmutter
Your brain… weighs three pounds and has one hundred thousand miles of blood vessels. contains more connections than there are stars in the Milky Way. is the fattest organ in your body. could be suffering this very minute without your having a clue.
~ David Perlmutter
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the same pathway that turns on BDNF production can be activated by intermittent fasting. We'll
~ David Perlmutter
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When asked to comment on the results, UCLA researcher Beatrice Golomb said, "Regarding statins as preventive medicines, there are a number of individual cases in case reports and case series where cognition is clearly and reproducibly adversely affected by statins."30 Golomb further added that various studies have demonstrated that statins either negatively affected cognition or were neutral, and that no trial has ever shown a positive outcome.
~ David Perlmutter
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omega-6 fats, which are found in many vegetable oils, including safflower oil, corn oil, canola oil, sunflower oil, and soybean oil; vegetable oil represents the number one source of fat in the American diet. According
~ David Perlmutter
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people whose blood sugar is on the high end of the "normal range" have a much greater risk for brain shrinkage.12 This ties directly into the story of type 3 diabetes.
~ David Perlmutter
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hunter-gatherer ancestors consumed omega-6 and omega-3 fats in a ratio of roughly 1:1.
~ David Perlmutter
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some experts believe our increased consumption of brain-healthy omega-3 fatty acids was responsible for the threefold increase in the size of the human brain). The
~ David Perlmutter
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people with celiac have significantly increased production of free radicals, and they exhibit free radical damage to their fat, protein, and even DNA.16 In addition, they also lose their ability to produce antioxidant substances in the body as a result of the immune system's response to gluten. In particular, they have reduced levels of glutathione, an
~ David Perlmutter
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Coconut oil, from which we derive MCTs, is a rich source of an important precursor molecule for beta-hydroxybutyrate and is a helpful approach to treating Alzheimer's disease.24
~ David Perlmutter
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Depression and anxiety are often severe in patients with gluten sensitivity.7, 8 This is primarily due to the cytokines that block production of critical brain neurotransmitters like serotonin, which is essential in regulating mood.
~ David Perlmutter
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Although microbial testing kits are starting to emerge on the market,
~ David Perlmutter
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ketogenic diet has also been shown to reduce amyloid in the brain,25 and it increases glutathione, the body's natural brain-protective antioxidant, in the hippocampus.26 What's more, it stimulates the growth of mitochondria and thus increases metabolic efficiency.27
~ David Perlmutter
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The neurons in the gut are so innumerable that scientist are now calling the totality of them "the second brain"... In fact, recent research is revaling that our second brain may not be second at all. It can act independently from the main brain and control many functions without the brain's input or help.
~ David Perlmutter
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But a caveat: Once free radicals damage the LDL molecule, it's rendered much less capable of delivering cholesterol to the brain. In addition to oxidation destroying the LDL's function, sugar can also render it dysfunctional by binding to it and accelerating oxidation. And when that happens, LDL is no longer able to enter the astrocyte, a cell charged with nourishing neurons. In
~ David Perlmutter
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ketones block the apoptotic pathway that would otherwise lead to self-destruction of brain cells.
~ David Perlmutter
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Warning: Drugs used to treat ADHD have resulted in cases of permanent Tourette's syndrome. Science has been documenting this since the early 1980s.10 Now that we have the research to prove the powerful effect of going gluten-free, it's time we change—no, make—history.
~ David Perlmutter
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As reported in the New England Journal of Medicine in 2013, even slight elevations of blood sugar that are far below the diabetes range have been shown to significantly increase the risk for the development of untreatable dementia.7
~ David Perlmutter
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gluten breaks down in the stomach to become a mix of polypeptides that can cross the blood-brain barrier. Once they gain entry, they can then bind to the brain's morphine receptor to produce a sensorial high. This
~ David Perlmutter
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researchers investigated the association between curry consumption level and cognitive function in elderly Asians.7 Those who ate curry "occasionally" and "often or very often" scored much better on specific tests designed to measure cognitive function than did people who "never or rarely" consumed curry.
~ David Perlmutter
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babies who are regularly breast-fed when they are first introduced to foods containing gluten have been shown to cut their risk of developing celiac disease by 52 percent, compared with those who are not being breast-fed.
~ David Perlmutter
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Brain dysfunction starts in your daily bread, and I'm going to prove it. I'll state it again because I realize it sounds absurd: Modern grains are silently destroying your brain.
~ David Perlmutter
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Sadece hareket etmek beyniniz için herhangi bir bulmacadan, matematik denkleminden,macera kitab?ndan, hatta dü?ünmekten daha yararl?d?r. Aerobik egzersizler sadece ömrü uzatmakla kalmaz, beynin "büyüme hormonu" olan BDNF'yi kodlayan genleri de harekete geçirir. Aerobik egzersizlerin ya?l?larda haf?za gerilemesini tersine çevirdi?i ve beynin haf?za merkezinde yeni beyin hücrelerinin olu?umu art?rd??? gözlemlenmi?tir.
~ David Perlmutter
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The bottom line is that if you want to reduce oxidative stress and the action of free radicals harming your brain, you have to reduce the glycation of proteins. Which is to say, you have to diminish the availability of sugar. Pure and simple.
~ David Perlmutter
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Anyone who's already been diagnosed with high cholesterol and prescribed a statin will be in for a rude awakening: I'm going to explain what's really going on in your body and tell you how to remedy this condition easily, deliciously, and without drugs.
~ David Perlmutter
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